Key result
Reverse-type takotsubo cardiomyopathy presents at a significantly younger age than other types (mean age 36 vs 62; P<.001) and is always associated with a triggering stress.
Why the study?
Are there clinical differences in patient characteristics and triggering stress between reverse-type Takotsubo cardiomyopathy and other variants?
Population
60 patients with Takotsubo cardiomyopathy identified from published case reports
Comparison
Reverse (inverted) type Takotsubo cardiomyopathy vs Classic and mid-cavitary types of Takotsubo…
Design
Systematic_review
Authors
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Prompts consideration of reverse-type variant in younger stressed patients; extends systematic characterization of Takotsubo subtypes.
Systematic Review (n=60)
Are there clinical differences in patient characteristics and triggering stress between reverse-type Takotsubo cardiomyopathy and other variants?
Absolute Event Rate: 36% vs 62%
p-value: p=<.001
Reverse or inverted Takotsubo cardiomyopathy presents at a significantly younger age and is universally associated with triggering stress compared to classic or mid-cavitary variants.
Ramaraj et al. (2010) conducted a systematic review in Takotsubo cardiomyopathy (n=60). Reverse (inverted) takotsubo cardiomyopathy vs. Classic and mid-cavitary takotsubo cardiomyopathy was evaluated on Age at presentation (p=<.001). Reverse-type takotsubo cardiomyopathy presents at a significantly younger age than other types (mean age 36 vs 62; P<.001) and is always associated with a triggering stress.
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