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August 1, 2003Journal of Biological ChemistryOpen Access

Inhibitor of Apoptosis Proteins Are Substrates for the Mitochondrial Serine Protease Omi/HtrA2

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Authors

SSSrinivasa M. SrinivasulaNational Institutes of HealthSGSanjeev GuptaOllscoil na Gaillimhe – University of GalwayPDPinaki DattaDefence Research Laboratory

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Srinivasula et al. (2003) studied this question.

synapsesocial.com/papers/6a95d2cffbcc90fe2d53977fhttps://doi.org/10.1074/jbc.c300240200
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  1. 1Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis2003 · 335 citations