Key result
Medication adherence in the first year of hypertension diagnosis was strongly associated with remaining adherent in the final follow-up year (OR 3.48).
Why the study?
The study aimed to examine medication adherence trends in newly diagnosed hypertensive patients and identify factors affecting their adherence.
Cohort (n=7,294)
Odds Ratio: 3.48 (95% CI 3.13–3.86)
p-value: p=<0.001
Medication adherence in the first year of hypertension diagnosis strongly predicts long-term adherence, highlighting the critical need for early patient education and intervention.
First-year adherence may guide targeted interventions in hypertension; extends observational data but leaves open whether early strategies improve long-term outcomes.
Objectives: This study aimed to examine medication adherence in newly diagnosed hypertensive patients and to investigate factors affecting their medication adherence. Methods: The present study used sample cohort database (DB) 2.0 provided by National Health Insurance Service and assessed 7,294 subjects meeting the inclusion criteria. The proportion of medication adherent and 8-year medication possession ratios (MPRs) according to general characteristics of subjects were analyzed. In addition, multiple regression and logistic regression analyses were used to examine relationship between MPR and medication adherence with its associated factors. All statistical analyses were completed with SAS statistical software version 9.4 (SAS Institute Inc., Cary, NC, USA) and p-value < 0.05 was considered to indicate statistical significance. Results: The proportion of medication adherent increased from 64.5% in the 1st year to 67.9% in the final follow-up year (maximum in the 7th year, 68.1%). Mean MPRs according to general characteristics of subjects were the lowest in the 2nd-3rd year. Medication adherence in newly diagnosed hypertensive patients was associated with age, complication, and MPR in the 1st year. The regression analyses suggested that MPR in the 1st year explained both the final and overall follow-up medication adherence 12.9% and 37.4%, respectively. In addition, medication adherents in the 1st year were more likely to remain as so in the final year (odds ratio, OR = 3.48). Conclusions: The findings suggested medication adherence in the early year of diagnosis is associated with the final and overall medication adherence in newly diagnosed hypertensive patients. It is necessary for medical institution and community to work together to establish education system for patients with hypertension at the initial stage of diagnosis.
No takes yet. Share an insight, caveat, or question.
Park et al. (2019) conducted a cohort in Newly diagnosed hypertension (n=7,294). Medication adherence in the 1st year (MPR ≥ 80%) vs. Medication non-adherence in the 1st year (MPR < 80%) was evaluated on Medication adherence in the final follow-up year (MPR ≥ 80%) (OR 3.48, 95% CI 3.13-3.86, p=<0.001). Medication adherence in the first year of hypertension diagnosis was strongly associated with remaining adherent in the final follow-up year (OR 3.48).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: