Interference Between Gram-Positive Microorganisms in Dental Plaque

Interference between gram-positive microorganisms indigenous to dental plaque was demonstrated in vitro on solid and liquid media. Data indicate that Streptococcus sanguis produces a broad inhibitory spectrum on other nonhemolytic streptococci, lactobacilli, corynebacteria, and actinomycetes. Certain Corynebacterium species and Lactobacillus casei inhibit the growth of Rothia dentocariosa and Actinomyces species. No inhibition by A viscosus, A naeslundii, or Rothia dentocariosa was demonstrable.