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On‐demand drug delivery is one of the main research directions of the drug delivery system (DDS). At present, with the development of various stimulus‐responsive materials and technology, it is possible to regulate drug release through various external or internal stimuli. Among them, electrical stimulation DDS has great potential due to its easy combination with sensor or microchip and precise time and space controlled‐release ability. At the same time, with the rapid growth of research in self‐powered devices, the self‐powerbility of electrical stimulation DDS has also received a lot of attention. In this review, the current biomaterials used in electrical stimulation DDS, such as conducting polymers, electroconductive hydrogels, carbon‐based nanomaterials, metal, and semiconductors are first introduced. Further the route of administration and recent advances of electrical stimulation DDS is summarized. The development and classification of self‐powered devices used in DDS are highlighted. In the end, the major challenges and future perspectives of electric stimuli‐responsive DDS are discussed.
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Xu et al. (2021) studied this question.
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