Key result
Prophylactic use of anticholinergic agents to prevent bradycardia during laparoscopic gynaecological surgery lacks supporting evidence, based on a systematic review of 8 studies.
Why the study?
Bradycardia and cardiac arrest are recognised complications of laparoscopic gynaecological surgery, but the role of anticholinergic agents in preventing bradycardia from peritoneal insufflation is less well defined.
Does the prophylactic use of anticholinergic agents prevent clinically significant bradycardia in women undergoing laparoscopic gynaecological surgery?
Systematic Review
Does the prophylactic use of anticholinergic agents prevent clinically significant bradycardia in women undergoing laparoscopic gynaecological surgery?
There is currently insufficient evidence to support the routine prophylactic use of anticholinergic agents to prevent bradycardia during laparoscopic gynecological surgery.
Answers are grounded in this paper and cite their sources.
Insufficient evidence precludes routine prophylaxis; leaves open whether targeted anticholinergics prevent bradycardia in this setting.
Bradycardia and cardiac arrest are recognised complications of laparoscopic gynaecological surgery. Anticholinergic agents are indicated in the treatment of perioperative bradyarrhythmia; however, their role in the prevention of bradycardia as a result of insufflation of the peritoneum is less well defined. This article systematically reviewed the literature with respect to the role of anticholinergic agents in the prevention of clinically significant bradyarrhythmia during laparoscopic gynaecological surgery. Eight studies were included for review following an extensive database search. This review highlights the paucity of evidence supporting the prophylactic use of anticholinergic agents in preventing clinically significant bradycardia in women undergoing laparoscopic gynaecological surgery.
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Steer et al. (2019) conducted a systematic review in bradycardia during laparoscopic gynaecological surgery. Anticholinergic agents was evaluated on clinically significant bradyarrhythmia. Prophylactic use of anticholinergic agents to prevent bradycardia during laparoscopic gynaecological surgery lacks supporting evidence, based on a systematic review of 8 studies.
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