Key result
Elevated cardiac troponin levels in patients with atrial fibrillation predict worse outcomes and greater cardio-embolic risk independently of other known risk factors.
Why the study?
What is the prognostic significance of elevated cardiac troponin levels in patients with atrial fibrillation?
What is the prognostic significance of elevated cardiac troponin levels in patients with atrial fibrillation?
This review explores the prognostic significance of elevated cardiac troponin levels in patients with atrial fibrillation, a common scenario outside of acute coronary syndromes.
Cardiac troponin assays have provided a significant contribution for the early diagnosis of cardiovascular events. There is significant evidence about the association between the absolute value of elevated cardiac troponin levels with the prognosis of patients with chest pain. However, it is well-known that elevated cardiac troponin levels may occur in situations other than acute coronary syndromes, as it happens with atrial fibrillation. The significance and prognosis of this elevation are not entirely clear. We review the evidence about the meaning of such elevation in the setting of atrial fibrillation.
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Costabel et al. (2017) conducted a review in Atrial Fibrillation. Elevated cardiac troponin vs. Normal or undetectable cardiac troponin was evaluated. Elevated cardiac troponin levels in patients with atrial fibrillation predict worse outcomes and greater cardio-embolic risk independently of other known risk factors.
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