Key result
COVID-19 is associated with acute and chronic cardiovascular manifestations, including myocardial injury in approximately 20% of patients, which relates to worse clinical outcomes and mortality.
Why the study?
Although COVID-19 significantly involves the cardiovascular system, mechanisms of myocardial injury, mixed imaging findings, and the duration and significance of persistent post-acute changes remain unclear.
COVID-19 causes significant acute and chronic cardiovascular complications, with myocardial injury occurring in about 20% of patients and correlating with increased mortality.
Answers are grounded in this paper and cite their sources.
Myocardial injury may flag higher-risk acute COVID-19 cases; leaves open whether targeted interventions alter outcomes.
COVID-19 has shown significant morbidity with the involvement of multiple systems, including the cardiovascular system. Cardiovascular manifestations in the acute phase can include myocardial injury itself, myocardial infarction, venous thromboembolic events, myocarditis, Takotsubo syndrome, and different arrhythmic events. Myocardial injury defined by the rise of cardiac biomarkers in blood has been found in multiple studies with a prevalence of about 20%. Its presence is related to worse clinical outcomes and in-hospital mortality. The mechanisms of myocardial injury have been the subject of intense research but still need to be clarified. The characterization of the cardiac affectation with echocardiography and cardiac magnetic resonance has found mixed results in different studies, with a striking incidence of imaging criteria for myocarditis. Regarding post-acute and chronic follow-up results, the persistence of symptoms and imaging changes in recovered COVID-19 patients has raised concerns about the duration and the possible significance of these findings. Even though the knowledge about this disease has increased incredibly in the last year, many aspects are still unclear and warrant further research.
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Arévalos et al. (2021) conducted a review in COVID-19. COVID-19 was evaluated on Myocardial injury. COVID-19 is associated with acute and chronic cardiovascular manifestations, including myocardial injury in approximately 20% of patients, which relates to worse clinical outcomes and mortality.
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