Chemotherapy of Bacterial Endocarditis

Article1 December 1941CHEMOTHERAPY OF BACTERIAL ENDOCARDITISRALPH A. KINSELLA, F.A.C.P.RALPH A. KINSELLA, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-6-982 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe treatment of bacterial endocarditis by chemical agents has been under consideration for many years, and the literature before sulfanilamide contains many reports of cures.The reproduction of the disease in dogs1, 2, 3 and its cure following the use of merthiolate intravenously4 and sulfanilamide orally4 created a hope that such agents could be successful in human cases. With the failure of merthiolate and the extended interest in the use of sulfonamide drugs in other fields of coccal infection, there has been renewed study of the use of these sulfonamide drugs in all forms of bacterial endocarditis.A glance at...Bibliography1. KINSELLASHERBURNE RACC: Experimental production of streptococcus endocarditis with glomerular nephritis, Proc. Soc. Exper. Biol. and Med., 1923, xx, 252-256. CrossrefGoogle Scholar2. NEDZEL E: Experimental endocarditis, Arch. Path., 1937, xxiv, 143-200. Google Scholar3. FRIEDMANKATZHOWELL MLNK: Experimental endocarditis due to Streptococcus viridans , Arch. Int. Med., 1938, lxi, 95-118. CrossrefGoogle Scholar4. KINSELLAMUETHER RARO: Experimental streptococcus endocarditis, Arch. Int. Med., 1938, lxii, 247-270. CrossrefGoogle Scholar5. LIPPMANN K: Subacute bacterial endocarditis case; new method of treatment, New York State Jr. Med., 1940, xxxx, 524-528. Google Scholar6. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA Review of Thimerosal (Merthiolate) and its Ethylmercury Breakdown Product: Specific Historical Considerations Regarding Safety and EffectivenessAntimicrobial treatment of infective endocarditis caused by viridans streptococci highly susceptible to penicillin: historic overview and future considerationsClinical Course of Severe Poisoning with ThiomersalSix cases of poisoning after a parenteral organic mercurial compound (Merthiolate)Treatment of Bacterial Endocarditis 1 December 1941Volume 15, Issue 6Page: 982-986KeywordsChemotherapyDrugsEndocarditisSulfonamide ePublished: 1 December 2008 Issue Published: 1 December 1941 PDF downloadLoading ...