Key result
Progressive maximal physical effort significantly increased superoxide anion (4.18 vs 4.01 at rest, p<0.05) and blood lactate (4.55 vs 1.95 at rest) in elite soccer players.
Why the study?
Does progressive maximal physical effort alter oxidative stress markers in elite soccer players?
Observational (n=19)
Does progressive maximal physical effort alter oxidative stress markers in elite soccer players?
Absolute Event Rate: 4.18% vs 4.01%
p-value: p=<0.05
Progressive maximal exercise in elite athletes alters oxidative stress markers, with the respiratory compensation point potentially playing a crucial role in signal transduction.
May signal elevated oxidative stress during maximal effort in elite athletes; hypothesis-generating for respiratory compensation point in redox signaling.
Some side-effects of excessive physical training are ascribed to reactive oxygen species production. In this work we investigated the effects of progressively imposed maximal physical effort (levels I to V), using progressive maximal exercise test, on peripheral blood lactate, NO (through NO2-), superoxide anion (O2-) and methemoglobin (MetHb) in a group of 19 elite soccer players. Blood lactate (mmol/L) was increased (4.55, level V vs. resting level, 1.95). The basal production of NO2- was in the direct relation with O2 consumption. Significant increase (p<0.05) in O2- values at effort level I (4.18) as compared to the resting value (4.01), and the significant increase (p<0.01 or p<0.05) in the MetHb (%) was found between II (18.79) and III (19.63) or between II and IV (19.24) effort levels, respectively. The regression lines of NO2- and O2- crossed at the level of the respiratory compensation point (RC), suggesting that RC could be of a crucial importance not only in the anaerobic and aerobic metabolism but in mechanisms of signal transductions as well. The results could be of the theoretical interest and also useful in designing an athlete training strategy.
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Jakovljević et al. (2011) conducted an observational in Healthy elite athletes (n=19). Progressive maximal physical effort vs. Resting level was evaluated on Superoxide anion (O2-) levels at effort level I (p=<0.05). Progressive maximal physical effort significantly increased superoxide anion (4.18 vs 4.01 at rest, p<0.05) and blood lactate (4.55 vs 1.95 at rest) in elite soccer players.
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