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1) 2-Methylmercapto-4-methylpyrimidine, 2-hydroxy-4-methyl-pyrimidine hydrochloride and 2-chloro-4-methylpyrimidine were synthesized.2) 2-Sulfanilamido-4-methylpyrimidine (Sulfamerazine) was synthesized with a good yield by the condensation of N4-acetyl-sulfanilamide and 2-chloro-4-methylpyrimidine under the presence of alkali carbonate.
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Matsukawa et al. (1949) studied this question.
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