Key result
Preoperative magnesium sulfate infusion resulted in comparable serum cardiac troponin levels compared to control in parturients with moderate preeclampsia undergoing elective cesarean section.
Why the study?
Does preoperative magnesium sulfate infusion reduce serum cardiac troponin in moderate preeclamptic parturients undergoing elective cesarean section?
RCT (n=50)
randomized
Does preoperative magnesium sulfate infusion reduce serum cardiac troponin in moderate preeclamptic parturients undergoing elective cesarean section?
Answers are grounded in this paper and cite their sources.
Preoperative magnesium sulfate infusion does not significantly affect postoperative serum cardiac troponin levels in moderate preeclamptic women undergoing elective cesarean section.
This study was designed to investigate and compare the effect of preoperative Mg sulfate infusion on serum cardiac troponin (cTn) in moderate preeclampsia undergoing elective cesarean section. A total of fifty parturients having moderate preeclampsia scheduled for elective cesarean section were included. They were randomly allocated into two equal groups 25 each, magnesium group (GMg) received preoperative magnesium sulfate infusion and control group (GC) then both received spinal anesthesia, serum troponin measured preoperative then at 6, 12 and 24 h postoperative. Mean arterial pressure and heart rate were also recorded. Baseline serum cardiac troponin was higher above normal and was comparable at the rest of times in both groups. Mean arterial pressure readings were significantly lower in GMg compared to GC at induction of spinal, skin incision and skin closure (P < 0.05) and were comparable at the rest of times. Serum cardiac troponin (cTn) levels were comparable in parturients received magnesium sulfate infusion preoperatively with those did not receive magnesium sulfate.
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Elzayyat et al. (2014) conducted an RCT in moderate preeclampsia (n=50). preoperative magnesium sulfate infusion vs. control was evaluated on serum cardiac troponin (cTn). Preoperative magnesium sulfate infusion resulted in comparable serum cardiac troponin levels compared to control in parturients with moderate preeclampsia undergoing elective cesarean section.
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