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Available data on the reductive alkylation of amines with carbonyl compounds ? a key method for the preparation of secondary and tertiary amines ? are described systematically. The review provides information on the relevant reducing agents and catalysts and on the use of chiral catalysts in stereo- and enantiocontrolled reactions of amine synthesis. The effect of the reactant and catalyst structures on the reaction rates and chemo- and stereo(enantio)selectivity is considered. The bibliography includes 156 references.
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Гусак et al. (2014) studied this question.
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