DNA Molecules on GaP (100) Surfaces: Spectroscopic Characterization and Biospecificity Assessment

Mind the bioactive GaP: Carboxylic acid-terminated GaP(100) surfaces are used to capture DNA molecules. The well-packed mixed biotin-modified DNA and alkyl-chains self-assemble onto the substrate (see figure) and exhibit good reproducibility, specificity and bioactivity confirmed by the use of nanoparticles and Cy3 fluorophore conjugates with streptavidin.