The enantiodiscriminating polymerization of racemic cyclodextrin‐complexed N‐methacryloyl‐phenylalanine methyl ester is investigated. 1H NMR spectra of the complexes with methylated β‐cyclodextrin in D2O manifest splittings due to chiral recognition. The different stabilities of the diastereomeric complexes influence the kinetics of the homopolymerization, particularly at 0 °C. An enrichment of the residual N‐methacryloyl‐L‐phenylalanine methyl ester of 14 % was achieved after 21 h of polymerization.
No takes yet. Share an insight, caveat, or question.
Schwarz-Barac et al. (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: