Key result
Lifetime suicide attempts in patients with bipolar disorders were associated with higher cholesterol values, but were unrelated to metabolic syndrome.
Cross-Sectional (n=80)
In patients with bipolar disorder, suicide attempts were associated with higher cholesterol values but not metabolic syndrome, suggesting serum lipids are not suitable biological trait markers for predicting suicide attempts.
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Higher cholesterol warrants no change in suicide risk assessment for bipolar disorder; leaves open lipids as trait markers pending prospective studies.
OBJECTIVES: To assess the relationship between lifetime suicide attempts (SAs), serum lipid values, and metabolic syndrome (MetS) in patients with bipolar disorders (BPD). METHODS: Eighty patients with BPD took part in the study (M = 40.60 years). After psychiatric diagnosis, demographic data, SAs, and serum lipids were measured and MetS was calculated. RESULTS: 70% reported at least one suicide attempt. 52.5% suffered from MetS. Suicide attempters had higher cholesterol values. SAs were associated with a family history of suicide, current mood state, and lower educational level. SAs were unrelated to MetS. CONCLUSIONS: In patients with BPD, against expectations, the occurrence of SAs was associated with higher cholesterol values. Serum lipid values are not suitable as a biological trait marker to predict SAs.
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Shakeri et al. (2014) conducted a cross-sectional in Bipolar disorders (n=80). Lifetime suicide attempts vs. No lifetime suicide attempts was evaluated on Relationship between lifetime suicide attempts, serum lipid values, and metabolic syndrome. Lifetime suicide attempts in patients with bipolar disorders were associated with higher cholesterol values, but were unrelated to metabolic syndrome.
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