Key result
Kidney transplant resulted in significant improvement in cardiac dysfunction in a 21-year-old male recipient with end-stage renal disease.
Why the study?
Low ejection fraction in kidney transplant candidates is considered a contraindication, despite kidney transplant being known to reverse cardiac dysfunction in end-stage renal disease.
Does kidney transplant improve cardiac dysfunction in patients with end-stage renal disease?
Case Report (n=1)
Does kidney transplant improve cardiac dysfunction in patients with end-stage renal disease?
Kidney transplant may reverse cardiac dysfunction caused by uremic toxins in patients with end-stage renal disease, challenging the notion that low ejection fraction is an absolute contraindication.
Answers are grounded in this paper and cite their sources.
May support transplant in ESRD with low EF; leaves open generalizability beyond single cases.
Kidney transplant is known to reverse cardiac dysfunction in patients with end-stage renal disease, and low ejection fraction in kidney transplant candidates is considered to be a contraindication for transplant. We present a significant improvement in cardiac dysfunction after successful kidney transplant in a 21-year-old male recipient. Kidney transplant may be beneficial for cardiac function in transplant recipients who have impaired cardiac function prior to the procedure and caused by uremic toxins.
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Sayın et al. (2022) conducted a case report in End-stage renal disease with cardiac dysfunction (n=1). Kidney transplant was evaluated on Improvement in cardiac dysfunction. Kidney transplant resulted in significant improvement in cardiac dysfunction in a 21-year-old male recipient with end-stage renal disease.
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