What question did this study set out to answer?

Determine the stereochemical configuration and conformational geometry of cis- and trans-3,5-dimethylvalerolactone isomers.

December 1, 1974The Journal of Organic Chemistry

Configuration and conformation of cis- and trans-3,5-dimethylvalerolactones

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Authors

FCFrank I. CarrollResearch Triangle Park Foundation GMGordon N. Mitchell JBJoseph T. Blackwell

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Implication

Spectroscopic analysis demonstrates stereochemical conformation of cis- and trans-3,5-dimethylvalerolactones, indicating the structural preferences of substituted lactone rings.

Key Points

Determine the stereochemical configuration and conformational geometry of cis- and trans-3,5-dimethylvalerolactone isomers.
Synthesized and separated the cis and trans isomers of 3,5-dimethylvalerolactone.
Performed structural and stereochemical characterization to analyze ring conformation and substituent positioning.
Established the absolute configurations and relative stereochemistry of both cis- and trans-3,5-dimethylvalerolactone isomers qualitatively.
Identified preferred ring conformations governed by steric interactions of the 3- and 5-methyl substituents on the valerolactone core.

Cite This Study

Carroll et al. (1974) studied this question.

synapsesocial.com/papers/6a9632ef86d3e3388374dcc4 https://doi.org/10.1021/jo00940a020

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Implication

Spectroscopic analysis demonstrates stereochemical conformation of cis- and trans-3,5-dimethylvalerolactones, indicating the structural preferences of substituted lactone rings.

Configuration and conformation of cis- and trans-3,5-dimethylvalerolactones

Discussion

Member takes

Implication

Key Points

Cite This Study

Configuration and conformation of cis- and trans-3,5-dimethylvalerolactones

Discussion

Member takes

Implication

Key Points

Cite This Study

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