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March 26, 2005Journal of Natural Products

Majusculoic Acid, a Brominated Cyclopropyl Fatty Acid from a Marine Cyanobacterial Mat Assemblage

John B. MacMillan Tadeusz F. Molinski

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Abstract

The novel antifungal compound majusculoic acid was isolated from a cyanobacterial mat microbial community. The structure of majusculoic acid was solved by interpretation of mass spectrometric and NMR data and conversion to the corresponding methyl ester. Majusculoic acid exhibits antifungal activity against Candida albicans ATCC 14503 (MIC 8 microM).

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synapsesocial.com/papers/6a96334386d3e3388374dce4 https://doi.org/10.1021/np049596k

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