Answers are grounded in this paper and cite their sources.
Rice weevil pheromone sitophilure ((4R,5S)-5-hydroxy-4-methyl-3-heptanone) and its three diastereomers were synthesized in three steps, starting from 3-(trimethylsilyloxy)-1,3-pentadiene and propionaldehyde. Other optically active α-methyl β-hydroxy ketones can also be synthesized by the reported procedure.
No takes yet. Share an insight, caveat, or question.
Delas et al. (1998) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: