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January 1, 2003The Journal of AntibioticsOpen Access

IB-00208, a New Cytotoxic Polycyclic Xanthone Produced by a Marine-derived Actinomadura. I. Isolation of the Strain, Taxonomy and Biological Activites.

Leyre Malet‐Cascon Francisco Romero Fernando Espliego‐Vazquez D. G. GRAVALOS José Luis Fernández-Puentes

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Abstract

A new compound, IB-00208, has been isolated from the fermentation broth of an actinomycete isolated from a marine environment. The strain was identified as Actinomadura sp. by its chemical and phylogenetic characteristics. The compound shows cytotoxic activity on tumor cell lines and bactericidal activity against gram-positive bacteria.

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Malet‐Cascon et al. (2003) studied this question.

synapsesocial.com/papers/6a9634455ab83fbd48d7c5a5 https://doi.org/10.7164/antibiotics.56.219

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