Answers are grounded in this paper and cite their sources.
A unique strategy toward the synthesis of polysubstituted indolizines has been developed. When 2-pyridinyl-2-(2′-bromoallyl)-1-carboxylates were treated with Cs 2 CO 3, the starting material went through a methylenecyclopropane ring formation/opening cascade, and the corresponding indolizines were obtained in moderate to good yield as a single regioisomer.
No takes yet. Share an insight, caveat, or question.
Zhu et al. (2017) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: