Key result
Calcium regulates myosin VI activation by controlling the orientation and interactions of its binding protein calmodulin, linking motor activation to cargo binding in a stepwise process.
This commentary highlights a novel mechanism by which calcium regulates myosin VI activation through calmodulin reorientation, advancing the understanding of unconventional myosin motor regulation.
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
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Masters et al. (2016) reported an editorial. Calcium regulates myosin VI activation by controlling the orientation and interactions of its binding protein calmodulin, linking motor activation to cargo binding in a stepwise process.
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