Facile and Efficient Hypervalent Iodine(III)-Mediated meso-Functionalization of Porphyrins

Highly facile and efficient synthesis of a variety of meso-functionalized porphyrins was accomplished by PhI(OAc)(2)-NaAuCl(4) mediated direct nucleophilic substitution reactions of [5,10,15-triphenylporphyrinato]zinc(II) (Zn1) with different amines and thiophenols. When [5,15-dibromo-10,20-diphenylporphyrinato]zinc(II) (Zn12) was used as the starting porphyrin under similar conditions, the double nucleophilic substitution products were obtained in good yields.