The aim of this study was to test adjunctive insertion of 1% metronidazole gel into furcation areas during periodontal maintenance. Ten patients were selected with paired, contralateral, Class II or III furcation involvements that also bled on constant force probing. Bleeding on probing (BOP) and gingival crevicular fluid (GCF) were measured as experimental variables. Plaque was assessed by dark-field microscopy (DFM). Following routine subgingival maintenance of these sites, a syringe was used to insert metronidazole or placebo gels into the furcations. Sites were re-examined 1 and 3 months after baseline. There was little change in either BOP or GCF. Marked longitudinal changes were found by DFM for both experimental and control sites. Experimental sites were not significantly different when compared with controls at the 5% level of probability.
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Needleman et al. (1989) studied this question.
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