Why the study?
Left ventricular hypertrophy is an established risk factor for cardiovascular complications, but the role of left ventricular mass and geometry in coronary artery bypass grafting outcomes remains underexplored.
Does increased left ventricular mass index predict mortality and postoperative complications in patients undergoing elective coronary artery bypass grafting?
Cohort (n=494)
Does increased left ventricular mass index predict mortality and postoperative complications in patients undergoing elective coronary artery bypass grafting?
Increased left ventricular mass index in CABG patients is associated with impaired postoperative kidney function but does not significantly impact 30-day to 3-year mortality.
Background: This study explores the impact of left ventricular mass and geometry on the prognosis of patients undergoing coronary artery bypass grafting. Left ventricular hypertrophy is a known risk factor for cardiovascular complications, yet its role in surgical outcomes remains underexplored. Methods: A retrospective cohort of 494 elective coronary artery bypass grafting patients treated between 2013 and 2018 was analyzed. Left ventricular mass was calculated using the Devereux formula, and patients were divided into normal and increased left ventricular mass index groups. Mortality rates, postoperative complications, and echocardiographic parameters were evaluated. Elevated preoperative biomarkers, including creatinine and C-reactive protein, were observed in this group, with sustained impairment in postoperative kidney function. However, no significant differences in 30-day, 1-year, or 3-year mortality rates were detected. Conclusion: Left ventricular mass and geometry independently predict long-term outcomes in coronary artery bypass grafting patients. Targeted strategies to mitigate left ventricular remodeling may enhance postoperative outcomes. Future research should focus on therapeutic interventions to reverse adverse left ventricular changes and optimize patient survival and quality of life.
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Timur et al. (2025) conducted a cohort in Coronary artery disease requiring elective coronary artery bypass grafting (n=494). Increased left ventricular mass index vs. Normal left ventricular mass index was evaluated on 30-day, 1-year, and 3-year mortality rates.
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