SUMMARY The experimental transmission of bovine leukosis virus (blv)-infected whole blood was studied in 2 groups of Holstein calves. The 1st group of 4 blv-seronegative calves was given 10 μ1 of whole blood by either the im, iv, subcutaneous, or intradermal routes. All 4 calves seroconverted to blv within 8 weeks after they were inoculated. The 2nd group, also comprising 4 calves, was given the equivalent of 1 μl of whole blood by the described routes. These calves seroconverted to blv by 14 weeks after they were inoculated. The results indicated that small volumes of whole blood administered by 4 different routes were effective in the spread of blv.
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Evermann et al. (1986) studied this question.
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