In a 3-year period 179 renal transplant operations were performed, during which time a uniform regimen for preventing wound infections was used. The incidence of primary renal transplant wound infections was reduced to 1 per cent by administering a single high dose of broad-spectrum antibiotics intraoperatively as an adjunct to this regimen. Intraoperative antibiotic coverage has been a safe and effective measure for preventing primary transplant wound infections.
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Andrew C. Novick (1981) studied this question.
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