Key result
A 28-year-old man with an intramedullary spindle cell hemangioendothelioma of the thoracic spinal cord survived 48 months with tumor growth restraint and neurological improvement following partial surgical decompression, radiotherapy, and systemic interferon therapy.
Case Report (n=1)
No
Immunotherapy with interferon should be considered as a treatment modality for intramedullary hemangioendothelioma of the spinal cord after surgery and radiotherapy.
May support interferon after surgery and radiotherapy in rare intramedullary hemangioendothelioma; hypothesis-generating and should not yet change practice.
A 28-year-old Malay man presented with progressive paraparesis over a period of 6 months. Magnetic resonance imaging of the spine revealed a thoracic intramedullary spinal cord tumor at the T-7 level with homogeneous enhancement following intravenous gadolinium administration. Laminectomy and partial decompression of the tumor was performed. Histological examination of the tumor revealed features of spindle cell hemangioendothelioma. The patient was managed with limited field radiotherapy followed by systemic interferon therapy. Good neurological improvement was seen subsequently. The patient has survived 48 months with growth restraint at the primary site, although residual neurological deficit persists. Immunotherapy should be considered as a treatment modality for intramedullary hemangioendothelioma of the spinal cord after surgery and radiotherapy.
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Abdullah et al. (2002) conducted a case report in Intramedullary Spindle Cell Hemangioendothelioma of the Thoracic Spinal Cord (n=1). Surgery, radiotherapy, and systemic interferon therapy was evaluated on Neurological improvement and tumor growth restraint. A 28-year-old man with an intramedullary spindle cell hemangioendothelioma of the thoracic spinal cord survived 48 months with tumor growth restraint and neurological improvement following partial surgical decompression, radiotherapy, and systemic interferon therapy.
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