The effects of triorganotins on the 4th instar stage of Aedes aegypti larvae were evaluated. The most effective of the 15 triorganotins used in the study was tributyltin chloride with an LC50 value of 0.57 ± 0.07 mg dm−3. The low LC50 values obtained indicated that this class of compounds is an effective larvicide against the larvae of this species of mosquito. The toxicity of the compounds was found to be primarily dependent on the R group attached to the tin atom. The order of activity for the triorganotins tested was Bu > Ph > Cy > Me. However, a limited order, based on two series of the compounds tested, was also observed for the anionic X group on the tin atom. Copyright © 2000 John Wiley & Sons, Ltd.
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