Butynorate, an Effective and Safe Substance for the Removal of Raillietina cesticillus from Chickens

THE problem of obtaining satisfactory anthelmintics against cestodes is one that is still subject to considerable study. During the past several years several compounds have been reported in the literature as being effective in removing tapeworms from poultry. Guthrie and Harwood (1941); Guthrie, Powick and Blandell (1941); and Guthrie and Harwood (1944) reported that certain tin compounds possessed anthelmintic activity against some of the cestodes of poultry. They also found that tin soaps in combination with pelletierine hydrochloride were highly efficacious against Raillielina cesticillus, R. tetragona and Hymenolepis carioca. In 1948 the writer reported that hexachlorophene, 2,2′-dihydroxy-3,3′,5,5′,6,6′-hexachlorodiphenyl methane, was effective in removing Raillietina cesticillus from chickens. In the same year Guthrie and Harwood (1948) reported that phenyl mercuric compounds, and, in particular, phenyl mercuric phtbalate, were effective against Raillietina cesticillus. To a somewhat lesser extent it was also effective against Hymenolepis carioca and Davainea proglottina. For one reason or another . . .