Key result
A 65-year-old male developed an extremely rare primary angiosarcoma of the brain 43 years after receiving external beam radiotherapy for a pituitary adenoma.
Case Report (n=1)
No
This case report highlights an extremely rare occurrence of primary angiosarcoma of the brain following external beam radiotherapy.
May prompt consideration of radiation-induced angiosarcoma in post-radiotherapy brain lesions; leaves open questions on incidence and surveillance.
Primary angiosarcoma of the central nervous systemis unusual.We encountered a case of radiation-induced angiosarcoma of the brain. A 65-year-old male was referred to our hospital with drowsiness for the last 6 months. He had undergone radiation therapy for pituitary adenoma 43 years ago. An MRI revealed a right temporal lobe tumour that consisted of a well-demarcated haemorrhagic lesion and an avid contrast enhancement, with significant vasogenic oedema. Surgical resection was performed and a post-operative pathological diagnosis of an angiosarcoma was made. A Thorotrast-associated angiosarcoma has been, hitherto, the only reported case of radiation-induced angiosarcoma of the brain. We present an extremely rare case of primary angiosarcoma of the brain, occurring after external beam radiotherapy.
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Hoshiai et al. (2015) conducted a case report in Radiation-induced angiosarcoma of the brain (n=1). External beam radiotherapy was evaluated on Diagnosis of angiosarcoma. A 65-year-old male developed an extremely rare primary angiosarcoma of the brain 43 years after receiving external beam radiotherapy for a pituitary adenoma.
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