The Value to Clinical Medicine of Experimental Studies on the Liver

Editorial1 November 1937THE VALUE TO CLINICAL MEDICINE OF EXPERIMENTAL STUDIES ON THE LIVERALBERT M. SNELLALBERT M. SNELLSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-5-851 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is difficult for the clinician interested in hepatic disease to overestimate the debt owing to laboratory workers who have so diligently studied the pathologic physiology of the liver. Clinical knowledge of hepatic disease, having been almost at a standstill for fifty years, is now being immensely enriched by the contributions of physiologists and biological chemists who have, first, fully informed us of the functions of the liver and later demonstrated its reparative and regenerative properties, its extraordinary reserve functional capacity and, most recently, the activities of the organ in maintaining normal internal environment.A large part of the success...1 OPIEALFORD ELLB: The influence of diet upon necrosis caused by hepatic and renal poisons. I. Diet and the hepatic lesions of chloroform, phosphorus, or alcohol, Jr. Exper. Med., 1915, xxi, 1-20. CrossrefGoogle Scholar2 BOLLMANMANN JLFC: The physiology of the impaired liver, Ergebn. d. Physiol., 1936, xxxviii, 445-492. CrossrefGoogle Scholar3 DRAGSTEDTVAN PROHASKAHARM LRJHP: Observations on a substance in the pancreas (a fat metabolizing hormone) which permits survival and prevents liver changes in depancreatized dogs, Am. Jr. Physiol., 1936, cxvii, 175-181. CrossrefGoogle Scholar4 ALLANBOWIEMACLEODROBINSON FNDJJJWL: Behavior of depancreatized dogs kept alive with insulin, Brit. Jr. Exper. Path., 1924, v, 75-83. Google Scholar5 BESTFERGUSONHERSHEY CHGCJM: Choline and liver fat in diabetic dogs, Jr. Physiol., 1933, lxxix, 94-102. CrossrefGoogle Scholar6 ROOT HF: Diabetic coma and acute pancreatitis with fatty livers, Jr. Am. Med. Assoc., 1937, cviii, 777-780. CrossrefGoogle Scholar7 HOLMANMAHONEYWHIPPLE RLEBGH: Blood plasma protein given by vein utilized in body metabolism. II. A dynamic equilibrium between plasma and tissue proteins, Jr. Exper. Med., 1934, lix, 269-282. CrossrefGoogle Scholar8 BUTTKEYS HRA: Colloid osmotic pressure; studies of normal individuals and of those with hypoproteinemia, Proc. Staff Meet. Mayo Clinic, 1937, xii, 566-570. Google Scholar9 BOLLMAN JL: Unpublished data. Google Scholar10 QUICKSTANLEY-BROWNBANCROFT AJMFW: Study of coagulation defect in hemophilia and in jaundice, Am. Jr. Med. Sci., 1935, cxc, 501-511. CrossrefGoogle Scholar11 WESTPHAL K: Muskelfunktion, Nervensystem u. Pathologie der Gallenwege: I. Untersuchungen über den Schmerzanfall der Gallenwege und seine ausstrahlenden Reflexe, Ztschr. f. klin. Med., 1923, xcvi, 22-51. II. Experimentelle Untersuchungen über die nervöse Beeinflussung der Bewegungsvorgänge der Gallenwege, Ztschr. f. klin. Med., 1923, xcvi, 52-94. III. Die Motilitätsneurose der Gallenwege und ihrer Beziehungen zu deren Pathologie, zur Stauung, Entzündung, Steinbildung u.s.w., Ztschr. f. klin. Med., 1923, xcvi, 95-150. Google Scholar12 IVYVOEGTLINGREENGARD ACWLH: The physiology of the common bile duct; a singular observation, Jr. Am. Med. Assoc., 1933, c, 1319-1320. CrossrefGoogle Scholar13 IVYSANDBLOM ACP: Biliary dyskinesia, ANN. INT. MED., 1934, viii, 115-122. Google Scholar14 MCGOWANBUTSCHWALTERS JMWLW: Pressure in the common bile duct of man; its relation to pain following cholecystectomy, Jr. Am. Med. Assoc., 1936, cvi, 2227-2230. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1937Volume 11, Issue 5Page: 851-855KeywordsChemistsLiverLiver diseasesResearch laboratories ePublished: 1 December 2008 Issue Published: 1 November 1937 PDF downloadLoading ...