Why the study?
What is the frequency of seizures and associated cardiovascular changes resulting from local anesthetic-induced systemic toxicity in patients undergoing regional anesthesia?
Population
Patients undergoing brachial plexus, epidural, and caudal regional anesthetics
Comparison
Regional anesthesia with local anesthetics vs Different types of regional blocks and different…
Design
Cohort
Follow-up
Acute perioperative period
Authors
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Seizure risk varies by block type without cardiovascular collapse even with bupivacaine; leaves open optimal selection and prevention strategies.
What is the frequency of seizures and associated cardiovascular changes resulting from local anesthetic-induced systemic toxicity in patients undergoing regional anesthesia?
The frequency of local anesthetic-induced seizures varies significantly by block type, but the incidence of cardiovascular collapse following these seizures is low, even with bupivacaine.
Brown et al. (1995) studied this question.
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