Cyclizative carboboration of carbon−carbon triple bonds has been achieved with a wide range of organozirconium reagents, including alkenyl, aryl, and alkylzirconium, with chloroboranes tethered to alkynes in the presence of palladium catalysts. The carboboration takes two distinctive stereochemical courses depending upon the phosphine ligands used: PMe 3 induces highly selective cis -carboboration, while bulkier phosphines such as P t Bu 3, PCy 3, and PAr 3 induce trans -carboboration selectively.
No takes yet. Share an insight, caveat, or question.
Daini et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: