Recognition of cellular murine transplantation antigens by lymphoid cells could be blocked by antisera against recognition structures (RS). These antisera were provoked by the injection of parental strain lymph node cells in low doses into adult F1 hybrids. The activity of anti‐RS antisera was highly specific. Treatment of recognizing cells with a particular serum inhibited the reaction towards a given transplantation antigen but did not impair recognition of another histo‐compatibility antigen. Anti‐RS antisera could be neutralized only by absorption with lymphoid cells carrying the specific RS.
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Ramseier et al. (1971) studied this question.
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