Key result
Enterovirus D68 infection was associated with fatal acute flaccid myelitis in a 55-year-old immunocompromised woman, with viral genome detected in cerebrospinal fluid.
Case Report (n=1)
No
Immunocompromised adults may be at risk for enterovirus D68-associated neurologic complications such as acute flaccid myelitis.
May indicate EV-D68 neurologic risk in immunocompromised adults; leaves open need for confirmatory studies.
In Italy in 2016, acute flaccid myelitis developed in a woman who had received a hematopoietic stem cell transplant. Enterovirus D68 viral genome was detected in respiratory and cerebrospinal fluid samples, and the viral protein 1 sequence clustered with lineage B3. Immunocompromised adults may be at risk for enterovirus D68-associated neurologic complications.
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Giombini et al. (2017) conducted a case report in Acute flaccid myelitis (n=1). Enterovirus D68 infection was evaluated on Clinical outcome (mortality). Enterovirus D68 infection was associated with fatal acute flaccid myelitis in a 55-year-old immunocompromised woman, with viral genome detected in cerebrospinal fluid.
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