Key result
Among 25 swine carcasses with skin lesions and other symptoms, 3 (12%) tested positive for PCV-2, exhibiting lesions suggestive of porcine dermatitis and nephropathy syndrome.
Why the study?
Although PCV-2 has many disease manifestations, the study aimed to investigate the cutaneous and renal lesions in PCV-2 infected cases.
Observational (n=25)
Yes
Answers are grounded in this paper and cite their sources.
Characterizes PCV-2 cutaneous and renal lesions in Kerala swine; leaves open prevalence, causality, and management implications for herds.
Porcine circovirus type-2 (PCV-2), is a widely studied pathogen in the swine population during the last decade. Even though, PCV-2 has many disease manifestations, the objective of the current study was to investigate the cutaneous and renal lesions in PCV-2 infected cases. Swine carcasses presented for post-mortem examination with a history of skin lesions, inappetance, dyspnoea and diarrhoea, during September 2021 to April 2022 from different parts of Kerala were utilised in this study. The samples were collected and screened with Polymerase chain reaction (PCR) after which, histological and immunohistochemical examination were performed. Three samples were found positive for PCV-2 out of 25 samples using PCR. Microscopically, skin revealed congestion, haemorrhages and infiltration of mononuclear infiltration cells and neutrophils in dermis and spongiosis in epidermis. Kidney revealed haemorrhages, congestion, tubular necrosis and degenerative alterations, interstitial mononuclear cell infiltration with occasional glomerulitis and vasculitis in the renal pelvis. Localisation of PCV-2 antigen was observed in renal tissue and lymph node with immunohistochemistry. Altogether, these findings were suggestive of porcine dermatitis and nephropathy syndrome (PDNS) in pigs. These results indicate the importance of including PCV-2 in the differential diagnosis of cutaneous lesions caused by bacterial and viral etiologies in pigs.
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Joseph et al. (2023) conducted an observational in Porcine circovirus type-2 (PCV-2) infection (n=25). Porcine Circovirus Type-2 (PCV-2) infection was evaluated on PCV-2 positivity. Among 25 swine carcasses with skin lesions and other symptoms, 3 (12%) tested positive for PCV-2, exhibiting lesions suggestive of porcine dermatitis and nephropathy syndrome.
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