Macroporous glycidyl methacrylate (GMA)‐divinylbenzene (DVB) copolymer beads have been synthesized and the adsorption of bilirubin, albumin and other serum components were studied. The beads composed of DVB/GMA in the weight ratio of 75/25 provide an excellent bilirubin adsorption ability. When the surface of the beads was previously coated with albumin, discriminating adsorption of the bilirubin in the serum was attained and the adsorption of albumin was depressed. In addition, when the coated albumin was crosslinked with glutaraldehyde, the excellent bilirubin adsorption ability was maintained, however, an adsorption of albumin from the serum occurred.
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Kuroda et al. (1996) studied this question.
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