Enantioselective Construction of All‐Carbon Quaternary Stereogenic Centers by Using Phosphine Catalysis

The asymmetric construction of all‐carbon quaternary stereogenic centers represents one of the most‐challenging tasks in organic synthesis, and it has drawn continuous attention from the synthetic community. Asymmetric phosphine catalysis has progressed at an astonishingly rate over the past decade and it offers the efficient creation of a diverse range of structural architectures. In this Focus Review, synthetic methods based on phosphine catalysis for the enantioselective construction of all‐carbon quaternary stereogenic centers are highlighted.