Primary Hyperparathyroidism and Increased Cardiovascular Risk—A Review Article

Primary hyperparathyroidism (pHPT) is a common endocrine disease of the parathyroid gland tissues which leads to inappropriate overproduction of the Parathyroid Hormone (PTH).The symptoms of pHPT vary and they include renal stones, osteoporosis, constipation, and weakness secondary to hypercalcemia and hypophosphatemia.Moreover, it has been reported that patients with pHPT are at increased risk of death due to cardiovascular disease.Many research papers have shown that there is an increased mortality rate in patients with pHPT due to the effect of PTH on the heart.This review article is discussing the effect of pHPT on the cardiovascular system as it is a common cause of mortality.