In vitro experimental study demonstrates prevention of heat-induced lysozyme aggregation by PEG copolymers, suggesting potential for protein stabilization.
The heat-induced aggregation of lysozyme was prevented when heated in the presence of poly-sulfobetaine and PEG copolymers, which were also effective in easing the refolding of the denatured protein.
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Debas et al. (2022) studied this question.
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