Key result
Cardiac magnetic resonance imaging identified extensive macroscopic fatty infiltration of the myocardium in three pediatric patients with ARVC/D, allowing timely transplantation and survival.
Why the study?
Pathologic evaluation remains the gold standard for ARVC/D diagnosis, but CMRI offers an advancing noninvasive method to identify fibrofatty changes in pediatric patients.
Does cardiac magnetic resonance imaging (CMRI) identify macroscopic fibro-fatty infiltration in pediatric patients with ARVC/D?
Case Report (n=3)
Does cardiac magnetic resonance imaging (CMRI) identify macroscopic fibro-fatty infiltration in pediatric patients with ARVC/D?
CMRI is a valuable noninvasive tool for identifying macroscopic fibro-fatty infiltration in pediatric patients with ARVC/D, facilitating timely diagnosis and transplantation.
Answers are grounded in this paper and cite their sources.
Pediatric ARVC/D cases add pathologic detail; extends limited literature but leaves open noninvasive diagnostic validation in children.
Background: Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is an inherited, progressive form of cardiomyopathy, which is characterized by fibrofatty replacement of the myocardium. While the gold standard for diagnosis remains pathologic evaluation of biopsy, advances in noninvasive imaging, including cardiac magnetic resonance imaging (CMRI), have led to improved clinical diagnosis.Case report: We report three additional cases of pediatric patients that have pathologically confirmed ARVC/D with CMRI images, demonstrating extensive macroscopic fatty infiltration of the right and left ventricular myocardium. The identification using CMRI allowed timely transplantation and patient survival.Conclusion: Our study is designed to highlight how fibrofatty changes are minimal using CMRI in the pediatric population and how this can be a valuable tool to provide an additional method of diagnosis.
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Slesnick et al. (2019) conducted a case report in Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) (n=3). Cardiac magnetic resonance imaging (CMRI) was evaluated on Identification of macroscopic fatty infiltration. Cardiac magnetic resonance imaging identified extensive macroscopic fatty infiltration of the myocardium in three pediatric patients with ARVC/D, allowing timely transplantation and survival.
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