Urodynamic Correlates of Resolution of Reflux in Meningomyelocele Patients

No AccessJournal of UrologyPediatric Urology1 Aug 1997Urodynamic Correlates of Resolution of Reflux in Meningomyelocele Patients Sanjiv K. Agarwal, Gordon A. McLorie, Deepa Grewal, Byron D. Joyner, Darius J. Bagli, and Antoine E. Khoury Sanjiv K. AgarwalSanjiv K. Agarwal More articles by this author , Gordon A. McLorieGordon A. McLorie More articles by this author , Deepa GrewalDeepa Grewal More articles by this author , Byron D. JoynerByron D. Joyner More articles by this author , Darius J. BagliDarius J. Bagli More articles by this author , and Antoine E. KhouryAntoine E. Khoury More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)64558-0AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Resolution of reflux in meningomyelocele patients is a reflection of improved bladder storage. We correlated resolution of reflux with changes observed in sequential urodynamic studies. Materials and Methods: The study included 27 children with meningomyelocele born between 1975 and 1985 who presented with or developed vesicoureteral reflux. Resolution of reflux was observed during the 10-year followup period as they were treated with a regimen of clean intermittent catheterization and pharmaco-therapy. Urodynamic studies were performed when vesicoureteral reflux was present and subsequent to its resolution. The urodynamic parameters compared in the 2 studies included bladder capacity, pressure specific bladder volume, bladder compliance and leak point pressure. Results: Significant increases in bladder capacity, pressure specific bladder volume and bladder compliance were noted. Leak point pressure appeared to be decreased subsequent to resolution of reflux. Conclusions: Resolution of reflux in meningomyelocele patients correlates with changes in parameters of bladder storage observed on sequential urodynamic studies. References 1 : Determinants of hydronephrosis and renal injury in patients with myelomeningocele.. J. Urol.1988; 140: 1289. Abstract, Google Scholar 2 : Outcome analysis of vesicoureteral reflux in children with myelodysplasia.. J. Urol.1997; 157: 980. Abstract, Google Scholar 3 : Bladder capacity (ounces) equals age (years) plus 2 predicts normal bladder capacity and aids in diagnosis of abnormal voiding patterns.. J. Urol.1983; 129: 347. Abstract, Google Scholar 4 : The sensitivity of pressure specific bladder volume versus total bladder capacity as a measure of bladder storage dysfunction.. J. Urol.1994; 152: 1578. Abstract, Google Scholar 5 : Bladder compliance in myelomeningocele children.. J. Urol.1989; 141: 1404. Google Scholar 6 : The value of leak point pressure and bladder compliance in the urodynamic evaluation of myelomeningocele patients.. J. Urol.1990; 144: 1440. Abstract, Google Scholar 7 : Prognostic value of urodynamic testing in myelodysplastic patients.. J. Urol.1981; 126: 205. Link, Google Scholar 8 : Relevance of detrusor hyperreflexia, vesical compliance and urethral pressure to the occurrence of vesicoureteral reflux in myelodysplastic patients.. J. Urol.1992; 147: 413. Abstract, Google Scholar 9 : Outcome of reflux in children with myelodysplasia managed by bladder pressure monitoring.. J. Urol.1994; 152: 1574. Abstract, Google Scholar 10 : Renal scarring and vesicoureteral reflux in children with myelodysplasia.. J. Urol.1990; 144: 541. Abstract, Google Scholar 11 : Bladder augmentation in patients with neurogenic bladder and vesicoureteral reflux.. J. Urol.1991; 146: 563. Abstract, Google Scholar 12 : Conservative bladder treatment in myelodysplasia. Differentiation of patients by cystomanometry.. Urol. Int.1976; 31: 93. Google Scholar 13 : Vesico-ureteral reflux in children with spina bifida and detrusor-sphincter dyssenergia.. Contr. Nephrol.1984; 39: 221. Google Scholar 14 : A bladder pressure management for myelodysplasia-clinical outcome.. J. Urol.1988; 140: 1499. Abstract, Google Scholar 15 : Upper urinary tract deterioration in patients with myelodysplasia and detrusor hypertonia: a followup study.. J. Urol.1983; 129: 829. Google Scholar 16 : Vesicoureteral reflux in children with spina bifida: natural history and results of treatment.. J. Urol.1986; 136: 329. Abstract, Google Scholar 17 : The value of urodynamic evaluation in newborns with myelodysplasia.. J.A.M.A.1984; 252: 650. Google Scholar 18 : Urethral dilation improves bladder compliance in children with myelomeningocele and high leak point pressures.. J. Urol.1990; 144: 430. Abstract, Google Scholar 19 : Nonsurgical management of threatened upper urinary tracts and incontinence in children with myelomeningocele.. J. Urol.1994; 152: 1582. Abstract, Google Scholar Division of Urology, Department of Surgery, The Hospital for Sick Children, Toronto, Canada.© 1997 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byShiroyanagi Y, Suzuki M, Matsuno D and Yamazaki Y (2018) The Significance of 99mTechnetium Dimercapto-Succinic Acid Renal Scan in Children With Spina Bifida During Long-Term FollowupJournal of Urology, VOL. 181, NO. 5, (2262-2266), Online publication date: 1-May-2009.Müller L, Abrahamsson K, Sillén U, Jacobsson B, Odén A and Hellström M (2018) Ultrasound Assessment of Detrusor Thickness in Children and Young Adults with MyelomeningoceleJournal of Urology, VOL. 175, NO. 2, (704-708), Online publication date: 1-Feb-2006. Volume 158Issue 2August 1997Page: 580-582 Advertisement Copyright & Permissions© 1997 by American Urological Association, Inc.MetricsAuthor Information Sanjiv K. Agarwal More articles by this author Gordon A. McLorie More articles by this author Deepa Grewal More articles by this author Byron D. Joyner More articles by this author Darius J. Bagli More articles by this author Antoine E. Khoury More articles by this author Expand All Advertisement PDF downloadLoading ...