The prognostic value of normal myocardial perfusion spect with positive coronary angiography

BACKGROUND: Normal exercise SPECT studies are associated with a low event rate. The association of the negative SPECT and positive coronary angiography with the results for the longtime follow up was determined. MATERIAL AND METHODS: 45 patients were included into the study. All patients had normal SPECT study and positive angiography in the ≤ 6 months after SPECT. 20 of them were women.Six patients had diabetes mellitus, 8 was smokers. Two patients had had left main coronary artery and 12 had multivessel disease. Baseline clinical risk factors were recorded for each patients and compared to outcomes. RESULTS: There were no deaths in the study group in the followup period. One myocardial infarct occurred in patient with multivessel disease and five more angioplasties with stents were performed in the long term follow up due to progression of coronary stenosis. CONCLUSIONS: We observed that the normal SPECT with positive ECG pattern is infrequent and has a very good prognostic value However, the long-term survival among a patient cohort with a normal exercise SPECT study is influenced by the number of concomitant CAD risk factors. We conclude that there is an importance of modifying CAD risk factors among patients with a normal SPECT.