This Perspective article highlights the recent development of mesoionic N-heterocyclic olefins (mNHOs), where the exo-cyclic olefinic carbon is not bonded to strongly electron-withdrawing groups. The unquenched basicity and nucleophilicity of the exo-cyclic olefinic carbon make mNHOs strong σ-donors and enable unique reactivity patterns.
No takes yet. Share an insight, caveat, or question.
Liang et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: