Hospitalizations associated with rotavirus gastroenteritis in Spain, 2001–2005

BACKGROUND: This study aims to describe and analyze hospital admissions in Spain due to rotavirus infections among children aged 5 years or under during the period 2001-2005, along with the associated health cost. METHODS: To update estimates of rotavirus hospitalizations rates in Spain, we conducted a retrospective study of 5 years of national hospitalization data associated with acute gastroenteritis using the Minimum Basic Data Set. RESULTS: During the study period, a total of 17.1% of all admissions due to acute gastroenteritis of any etiology in children aged < or = 5 years were attributable to rotavirus infection as determined by the rotavirus-specific International Classification of Diseases, ninth revision, Clinical Modification code. A mean incidence of 135 hospital admissions attributable to rotavirus per 100,000 children aged < or = 5 years was found. Hospitalizations associated with rotavirus had a marked winter-time seasonality. The estimated cost of hospital admission attributable to rotavirus has risen from 3 million euros estimated for 2001 to almost 7 million euros estimated in 2005. CONCLUSION: Rotavirus gastroenteritis remains an important cause of hospitalizations in Spanish children, mostly during the winter season.