Key result
Transcatheter edge-to-edge repair using the DragonFly system with clip deployment at a specific angle successfully reduced severe mitral regurgitation to mild with a pressure gradient of 5 mm Hg.
Why the study?
In patients with a relatively small mitral valve area, transcatheter edge-to-edge repair may risk inducing mitral stenosis.
Can TEER using the DragonFly system be safely and effectively performed in a patient with severe mitral regurgitation and a small mitral valve area?
Case Report (n=1)
No
Can TEER using the DragonFly system be safely and effectively performed in a patient with severe mitral regurgitation and a small mitral valve area?
TEER using the DragonFly system with specific angle deployment can successfully treat severe MR in patients with small mitral valve areas while controlling the transmitral pressure gradient.
Caution warranted for TEER with small mitral valve area; leaves open optimal selection thresholds for prospective study.
Introduction Transcatheter edge-to-edge repair has been proven to be safe and effective for mitral regurgitation. In patients with a relatively small mitral valve area, transcatheter edge-to-edge repair may risk inducing mitral stenosis. Case Summary A 76-year-old female patient presented with decompensated heart failure and severe mitral regurgitation. Transthoracic echocardiography revealed an effective regurgitant orifice area of 0.39 cm 2 . Transesophageal echocardiography revealed anterior leaflet prolapse between the A2-P2 region. The procedure was conducted successfully by using DragonFly system, and the clip was released at an angle of approximately 17°. Transesophageal echocardiography showed the mitral valve pressure gradient was 5 mm Hg and mild regurgitation. Discussion The DragonFly system can released safety deployment at a specific angle, which can achieve an effective balance between reducing reflux and controlling mitral valve pressure gradient.
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Lin et al. (2025) conducted a case report in Severe mitral regurgitation with small mitral valve area (n=1). Transcatheter edge-to-edge repair (TEER) using DragonFly system with specific angle clip deployment was evaluated on Mitral valve pressure gradient and regurgitation severity. Transcatheter edge-to-edge repair using the DragonFly system with clip deployment at a specific angle successfully reduced severe mitral regurgitation to mild with a pressure gradient of 5 mm Hg.
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