Key result
A 10-year-old male child developed cardiac dysrhythmia following a 5-day course of oral metronidazole (500 mg 3 times/day) for a dental abscess.
Case Report (n=1)
This case highlights a rare instance of potential metronidazole-induced QT prolongation and cardiac dysrhythmia in a pediatric patient.
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Alerts clinicians to possible metronidazole QT effects; case report leaves open arrhythmogenic risk.
Metronidazole is nitroimidazole antibiotic medication which has a specific activity against anaerobic bacteria and protozoa. In cardiology, the QT interval represents electrical depolarization and repolarization of the ventricles. A lengthened QT interval is a marker for the potential of ventricular tachyarrhythmia. Rare cases have been reported with QT prolongation in which metronidazole antibiotic had been used. The arrythmogenic properties of metronidazole is not yet clear. This case reports a 10-year-old male child of 30 kg body weight with no history of any chronic illness or drug allergy came to the dental clinic with facial swelling, which was diagnosed as dental abscess. He was given oral metronidazole (500 mg 3 times/day for 5 days).
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Badria et al. (2017) conducted a case report in Dental abscess (n=1). Metronidazole was evaluated on Cardiac dysrhythmia. A 10-year-old male child developed cardiac dysrhythmia following a 5-day course of oral metronidazole (500 mg 3 times/day) for a dental abscess.
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