Exfoliative Cytology in the Diagnosis of Stomach Cancer

Article1 December 1965Exfoliative Cytology in the Diagnosis of Stomach CancerDUANE W. TAEBEL, M.D., JOAO C. PROLLA, M.D., JOSEPH B. KIRSNER, M.D., F.A.C.P.DUANE W. TAEBEL, M.D.Search for more papers by this author, JOAO C. PROLLA, M.D.Search for more papers by this author, JOSEPH B. KIRSNER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-6-1018 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptConcern for the early diagnosis of cancer has been one of the main factors in the development of diagnostic methods for the examination of the upper gastrointestinal tract: X ray, endoscopy, and more recently, exfoliative cytology. The latter technique was advocated initially over 100 years ago by Beale (1) who, in 1858, examined vomitus by paraffin block technique. In 1909, Marini (2) conceived the idea that fresh material obtained by gastric lavage might contain better preserved malignant cells. He was able to obtain malignant cells in 32 of 37 gastric and esophageal carcinomas, a remarkable accomplishment considering that the preparations...References1. BEALE LS: The Microscope in Medicine, 2nd ed. J. & A. Churchill, Ltd., 1858. Google Scholar2. MARINI G: Über die diagnose des magencarcinomas auf grund der cytologischen untersuchung des spülwassers. Arch. Verdaumgskrankh 15: 251, 1909. CrossrefGoogle Scholar3. LOEPERBINET ME: Le cytodiagnostic des affections de l'estomac. Bull. Soc. Med. Hop. (Paris) 31: 563, 1911. Google Scholar4. PAPANICOLAOU GN: Atlas of Exfoliative Cytology. Harvard University Press, Cambridge, 1954. Google Scholar5. SCHADE RO: Gastric Cytology. Edward Arnold, Ltd., London, 1960. Google Scholar6. KLAYMANMASSEY MIBW: The cytologic diagnosis of gastric cancer by chymotrypsin lavage. Gastroenterology 29: 849, 1955. CrossrefMedlineGoogle Scholar7. MACDONALDBRANDBORGTANIGUCHIRUBIN WCLLLCE: Gastric exfoliative cytology. Lancet 2: 83, 1963. CrossrefGoogle Scholar8. PROLLATAEBELKIRSNER JDWJB: Current status of exfoliative cytology in diagnosis of malignant neoplasms of the esophagus. Surg. Gynec. Obstet. October, 1965. MedlineGoogle Scholar9. GIBBS DD: Gastric cytodiagnosis: a review and appraisal. Gut 1: 205, 1960. CrossrefMedlineGoogle Scholar10. RASKINKIRSNERPALMER HFJBWL: Role of exfoliative cytology in the diagnosis of cancer of the digestive tract. JAMA 169: 789, 1959. CrossrefMedlineGoogle Scholar11. BURNETTMACFARLANESCOTTKAY WPSSDAW: Carcinoma of the stomach. Brit. Med. J. 5175: 753, 1960. CrossrefGoogle Scholar12. STRANDJORDMOSELEYSCHWEINEFUS NMRDRL: Gastric carcinoma: accuracy of radiologic diagnosis. Radiology 74: 442, 1960. CrossrefMedlineGoogle Scholar13. PALMER WL: Cancer of the stomach. Rocky Mountain Med. J. 57: 40, 1960. MedlineGoogle Scholar14. VILARDELL F: Gastroenterology, 2nd ed., vol. I, edited by BOCKUS, H. L. W. B. Saunders Co., Philadelphia, 1963, pp. 772-4. Google Scholar15. YAMADA T: Basic study of the proteolytic enzyme lavage method in the gastric diagnosis, especially in the comparative analysis of the exfoliative tendency of malignant and benign epithelial cells. Acta Cytol. (Phila.) 8: 19, 1964. MedlineGoogle Scholar16. YAMADAMATSUMOTOSANKAWASEINO TSKY: Clinical evaluation of proteolytic enzyme lavage method in the gastric cytodiagnosis, especially in the detection of early cancer of the stomach. Acta Cytol. (Phila.) 8: 27, 1964. MedlineGoogle Scholar17. LUCAS PF: Lymph node smears in the diagnosis of lymphadenopathy: a review. Blood 10: 1030, 1955. CrossrefMedlineGoogle Scholar18. MORRISONSAMWICHRUBINSTEINSTITCHLOWE MAAJML: Lymph node aspiration. Amer. J. Clin. Path. 22: 255, 1952. CrossrefMedlineGoogle Scholar19. KLAYMANKIRSNERPALMER MIIBWL: Gastric malignant lymphoma: increasing accuracy in diagnosis. Gastroenterology 29: 536, 1955. CrossrefMedlineGoogle Scholar20. BLOCKLANCASTER DEGR: Adenocarcinoma of the cardioesophageal junction. Arch. Surg. (Chicago) 88: 852, 1964. CrossrefMedlineGoogle Scholar21. STOUT AP: Tumors of the Stomach. Armed Forces Institute of Pathology, Washington, D. C., 1953. Google Scholar22. PALUMBOSHARPE LTWS: Gastric ulcer: is it benign or malignant? Arch. Surg. (Chicago) 85: 705, 1962. CrossrefGoogle Scholar23. FRIDMAN EG: Cancer of a resected stomach: analysis of 194 cases. (8th International Cancer Congress, Moscow, July 22-28, 1962). Acta Un. Int. Cancr. 19: 1257, 1963. MedlineGoogle Scholar24. GIBBS DD: Carcinoma in the gastric remnant after partial gastrectomy for benign ulceration. Gut 3: 322, 1962. CrossrefMedlineGoogle Scholar25. SCHADE RO: Quoted by KOSS, L. G., DURFEE, G. R., in Diagnostic Cytology and Its Histopathological Basis. J. B. Lippincott Co., Philadelphia, 1961, p. 263. Google Scholar26. KLAYMANMASSEYPLETICKAGALAMBOSBRANDBORGKIRSNERPALMER MIBWSJTLJBWL: Cytological diagnosis of gastric cancer by chymotrypsin lavage. II. Detection of early malignancy. Gastroenterology 29: 854, 1955. CrossrefMedlineGoogle Scholar27. GRAHAM RM: Diagnosis of cancer of internal organs by Papanicolaou technique. Advances Intern. Med. 6: 59, 1954. MedlineGoogle Scholar28. PASSARELLISHEDDBERESSPIRO NMDPPH: Exfoliative cytology and early carcinoma of the stomach. Ann. Surg. 158: 144, 1963. CrossrefMedlineGoogle Scholar29. MACDONALDBRANDBORGTANIGUCHIBEHRUBIN WCLLLJECE: Exfoliative cytological screening for gastric cancer. Cancer 17: 163, 1964. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DUANE W. TAEBEL, M.D.; JOAO C. PROLLA, M.D.; JOSEPH B. KIRSNER, M.D., F.A.C.P.Affiliations: Chicago, IllinoisFrom the Department of Medicine, University of Chicago School of Medicine, Chicago, Ill.This study was supported in part by a research grant from the Illinois Department of Public Health.Portions of this study were presented before the Golden Anniversary Session of the American College of Physicians, March 22, 1965, Chicago, Ill.Requests for reprints should be addressed to Duane W. Taebel, M.D., Department of Medicine, University of Chicago School of Medicine, Chicago, Ill. 60637. 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